Growth hormone deficiency is lack of sufficient growth hormone in the body, which is one of the causes for short stature. Growth hormone is a protein that is naturally produced in the pituitary galnd in the brain. Growth hormone is responsible for normal, healthy growth in children. Children with growth hormone deficiency may be perfectly healthy otherwise. Sometimes growth hormone deficiency is part of a larger problem e.g. injury following a brain surgery. In all these children giving growth hormone restores the healthy growth and helps them attain their true height potential.
The growth hormone used for treatment is manufactured by recombinant DNA technology. This so-called recombinant hormone is an exact copy of the growth hormone that is normally produced in the body. It does not carry any contamination risk unlike older methods using pituitary extracts. It must be given as a daily injection, usually at bedtime. It is injected by a pen similar to insulin which makes it virtually painless. Unfortunately it cannot be given as a pill because, it is a protein and gets destroyed by the digestive juices in the stomach.
Recombinant growth hormone is being widely used for more than 20 years. With proper diagnosis and expert monitoring side effects are rare and mild. Over a lakh patients are treated with growth hormone every year across the globe.
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